Thames Valley Police was called to a 12-vehicle road traffic collision at just after 7am this morning near the Chalfont Viaduct.
It happened between junction 16 and 17 of the M25.
As a result of the collision, one person suffered a minor injury and was taken to Wexham Park Hospital in Slough.
All lanes were blocked for a short period of around 20 minutes while the vehicles were cleared.
One lane re-opened shortly after the collision, and all lanes re-opened.
An investigation into the collision is ongoing, and anyone with any information should call 101, quoting reference number 43200413916.